Day 1
9:00-9:05 Welcome Suzanne Tomlinson, Gulf Coast Consortia
Mehmet Sen, University of Houston
Convenor: Mehmet Sen, University of Houston
9:05-9:50 Keynote Presentation
How do Protein Domains of Low Sequence Complexity Create Dynamic Morphological Order Within Cells?
Steven McKnight, University of Texas Southwestern
Session I Scholars’ Choice
Convenor: Josephine Chu Ferreon, Baylor College of Medicine
9:50-10:10 Extrachromosomal DNA Amplifications Shape Tumor Heterogeneity and Spatial Organization in Human Brain Tumors
Kadir Caner Akdemir, MD Anderson Cancer Center
10:10-10:30 AI-assisted Directed Evolution of Immunogens
Jimmy Gollihar, Houston Methodist Research Institute
10:30-11:00 Vendor Networking Break-Event Hall
Session II Scholars’ Choice
Convenor: Josephine Chu Ferreon, Baylor College of Medicine
11:00-11:20 Native Mass Spectrometry of Membrane Channels and Transporters
Art Laganowsky, Texas A&M University
11:20-11:40 Control and Monitoring of Intact Brain with Noninvasive Neuroengineering
Jerzy Szablowski, Rice University
Session III Trainee Presentations, selected from abstracts
Convenor: Alexander Vela, University of Houston
11:40-11:55 Effector Domain Classification of Human Transcription Factors Using Unsupervised Learning
Eduardo Ayala, University of Houston
11:55-12:10 Unraveling the Structure of the Philadelphia Chromosome Using Super-Resolution Microscopy
Gabrielle Dewson, University of Texas Medical Branch
12:10-12:25 Biochemical Profiling and Structural Basis of ADAR1-Mediated RNA Editing
Xiangyu Deng, Rice University
12:25-12:45 Lightning Poster Talks even-numbered posters
Yousef Elmakdah, University of Houston
Elucidating the Structures and Binding Kinetics Associated with α-1, α-2, α-10, and α-11 Collagen-Binding Domains, Poster 2
Victoria Flores, UTMB
Global Knotting is Infrequent in the Salmonella Genome, Poster 4
Aravind Govindaraju, Rice University
Modeling Quantal and Ephaptic Transmission in Vestibular Dimorphic Neurons, Poster 6
Gundeep Kaur, MD Anderson Cancer Center
Structural Insights into HELLS and Its Interaction with CDCA7 and Non-B Form DNA, Poster 10
Chen-Yu Lo, Rice University
Cryo-EM Structures of the Plasmodium Falciparum Apicoplast DNA Polymerase, Poster 12
Sayantan Pradhan, University of Houston
Von Willebrand Factor Dimerizes Despite Absence of Prodomain, Poster 14
Aditi Singh, University of Texas Medical Branch, Galveston
Investigating Mechanisms of Cancer Cell Apoptosis with Low Frequency Ultrasound, Poster 18
Deepak Kumar Yadav, Houston Methodist Research Institute
Effects of Modified Nucleotide Bases on RNA 3D Structure, Poster 20
12:45-2:30 Lunch and poster presentation-Event Hall
12:45-1:30 Lunch
1:30-2:30 Poster presentation-even numbered posters
Convenor: Gül Zerze, University of Houston
2:30-3:00 Rising Star Plenary Speaker
Mapping Molecular Dynamics and Nanoscale Cellular Architectures in Health and Disease
Anna-Karin Gustavsson, Rice University
Session IV Scholars’ Choice
3:00-3:20 Engineering DNA Probes for Super-Resolution and Single-Molecule Proteomics
Mingjie Dai, Rice University
3:20-3:40 Integrin Conformation Under Tension: Mechanistic Insights into Transmigration
Travis Moore, University of Texas Health Science Center Houston
3:40-4:00 Senescent Cell and Animal Rejuvenation by Low Frequency Ultrasound
Michael Sheetz, University of Texas Medical Branch Galveston
4:00-4:30 Mechanisms of DNA Double-Strand Break Repair
Tanya T Paull, University of Texas Austin
4:30-5:30 Reception-Event Hall
Day 2
Convenor: Ewan McRae, Houston Methodist Research Institute
9:00-9:45 Keynote Presentation
Using Biophysical Tools to Study Amino-Acid Based Proton-Coupled Electron Transfer
Cecilia Tommos, Texas A&M University
Session V Scholars’ Choice
9:45-10:05 Force Generated by Blood Flow Triggers mTOR-dependent Mitochondrial Remodeling in Hematopoiesis
Pamela Wenzel, University of Texas Health Science Center Houston
10:05-10:25 DNA Hypomethylation and Genome Instability
Xiaodong Cheng, MD Anderson Cancer Center
10:25-10:45 A New Mechanical Model of the Nucleus
Tanmay Lele, Texas A&M University
10:45-11:05 Reenginnering CRISPR-Cas Effector Complexes
David Taylor, University of Texas Austin
11:05-11:30 Vendor Networking Break-Event Hall
Session VI
Convenor: Mehmet Sen, University of Houston
11:30-12:00 Rising Star Plenary Speaker
Mark Herzik, University of California, San Diego
12:00-12:25 Lightning Poster Talks odd-numbered posters
Angelina Albelo, University of Houston
Construct as a First Step to Determining Ligand Preferences For Next-Gen Drug Design, Poster 1
Viraj Ghosh, Rice University
Single Molecule Force-Extension Measurements of EWS-FLI1/DNA Co-condensates, Poster 5
Paola Gueva, University of Houston
Deciphering GPIbα-vWF Binding: A Structural Approach to Understanding Platelet Activation, Poster 7
Wesley Leung, Rice University
Characterization of Intrinsically Disordered Protein-Polymer Interactions with Fluorescence Polarization, Poster 11
Rulong Ma, University of Houston
The Tilting Motion of the Central Core Reveals the Transport Mechanism of the Sarco/endoplasmic Reticulum Ca2+-ATPase, Poster 27
Anthony Pastore, University of Texas Medical Branch
Protein Refolding of an Adhesion Molecule Relevant to Sensory Gating, Poster 13
Kosar Rahimi, University of Houston
Comparison of Advanced Sampling Techniques for Atomistic Scale Simulation of RNA Folding, Poster 15
Hasan Siddiqui, University of Houston
Conformational Dynamics of ICAM-1: Exploring the Role of G241R and K469E Mutations in Disease Pathogenesis, Poster 17
Justin Van Riper, Baylor College of Medicine
Novel Insights into the Structure and Activation of the SLFN14 Ribonuclease, Poster 19
Haiqing Zhao, UT Medical Branch Galveston
Proteome-scale Predictions of Protein-Protein Interactions for Human and E. coli, Poster 21
12:25-2:00 Lunch and poster presentation-Event Hall
12:20-1:00 Lunch
1:00-2:00 Poster presentation-odd numbered posters